To study the metabolism and absorption of endosulfan in carp, ^(14)C-¥á-endosulfan was treated with the LC_(10) concentration (4.5 §¶/L). In an in vivo test, endosulfan was metabolized (65¡80%) in tissues and endosulfan ether, endosulfan alcohol, endosulfan a-hydroxyether, and endosulfan lactone were identified, indicating that those are the main metabolites of detoxification in carp. The maximum levels of ^(14)C-endosulfan in the head, muscle, and gut occurred after 8 hr exposure. However, the maxima reached in the liver and kidneys after 30 min and 4 hr, respectively. Radioactivity in the tissue decreased rapidly 8 hr after treatment. The total amount of ^(14)C-endosulfan recovered in the liver, kidneys and gut of fish was about 80¡90% during the 8 hr treatment. The non-extractable radioactivity increased after 8 hr exposure (27¡31%). Endosulfan sulfate, the main degradation product in plant and mouse, was not detected during the test interval from tissues of the carp.
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