Àá½Ã¸¸ ±â´Ù·Á ÁÖ¼¼¿ä. ·ÎµùÁßÀÔ´Ï´Ù.
KMID : 0903519940370030194
Journal of the Korean Society of Agricultural Chemistry and Biotechnology
1994 Volume.37 No. 3 p.194 ~ p.202
In vivo Metabolism of Endosulfan in Carp(Cyprinus carpio L .)



Abstract
To study the metabolism and absorption of endosulfan in carp, ^(14)C-¥á-endosulfan was treated with the LC_(10) concentration (4.5 §¶/L). In an in vivo test, endosulfan was metabolized (65¡­80%) in tissues and endosulfan ether, endosulfan alcohol, endosulfan a-hydroxyether, and endosulfan lactone were identified, indicating that those are the main metabolites of detoxification in carp. The maximum levels of ^(14)C-endosulfan in the head, muscle, and gut occurred after 8 hr exposure. However, the maxima reached in the liver and kidneys after 30 min and 4 hr, respectively. Radioactivity in the tissue decreased rapidly 8 hr after treatment. The total amount of ^(14)C-endosulfan recovered in the liver, kidneys and gut of fish was about 80¡­90% during the 8 hr treatment. The non-extractable radioactivity increased after 8 hr exposure (27¡­31%). Endosulfan sulfate, the main degradation product in plant and mouse, was not detected during the test interval from tissues of the carp.
KEYWORD
FullTexts / Linksout information
Listed journal information